Hypoluxo is a town in Palm Beach County, Florida, United States. The population was 2,015 at the 2000 census. As of 2004, the population recorded by the U.S. Census Bureau is 2,599. The name "Hypoluxo" comes from the Seminole name for Lake Worth, roughly translated "water all 'round -- no get out." The lake was later renamed in honor of Seminole Indian War colonel William Jerkins Worth. However, the name "Hypoluxo" still was associated with the area on the south shores of the lake, as evidenced by its appearance on a 1841 War Department map.Hypoluxo Scrub Natural Area is a protected landscape.